It's best to choose based on factors like distance, reliability and downstream equipment:

• • SDI: Ideal for long cable runs and professional broadcast rigs. 
  • HDMI: Good for shorter runs (typically under 50 ft) and non-industrial setups. 
  • USB: Best for simple webcam-type streams or conferencing with cable runs under ~15 ft. 
  • IP/NDI: Great for flexible routing over LAN/WAN, remote studios, multi-device setups.